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法医病理学家纳里曼博士与一名摩托车手发生车祸，伤及他8岁的儿子。他提议将孩子带到附近的诊所，但这位父亲却拒绝了他的帮助。第二天早上，在他工作的医院里，纳里曼医生发现这个小男孩竟然死了……他面临着一个两难的困境：孩子死于车祸还是死于可疑的食物中毒？。民国乱世之秋，诸事纷变。景城警察署署长江月楼亦正亦邪，令走私犯罪分子闻风丧胆。于香港追查鸦片案件时，邂逅楚然与陈余之，三人成为好友。陈余之发现江月楼的躁郁症，江月楼从最初拒绝治疗到与陈余之交心。一个杀人，一个救人，价值观南辕北辙的两人互相救赎，成为惺惺相惜的好友。此外，军阀势力展君白、商会大亨赵璟明、流氓帮会周火等人不断制造麻烦，欲置江月楼于死地。三个好伙伴在一次次见招拆招中互相扶持成长，期间两大家族的秘密也渐渐浮出水面。。Two hundred years after Mary Shelley's novel the brilliant but mad Doctor (Thomas Kretschmann) has sustained his creature and himself over two centuries through genetic experimentation. In present-day America Detective O'Connor (Parker Posey) is investigating a series of horrific murders which leads her to the doctor and his creature. What she uncovers reveals the strange evolu...。